Gastric Bypass Surgery Decreases the Desire to Drink – Say What?

As many of you who routinely read my blog can imagine, the title of this study was bound to catch my attention.    Really?    Was someone actually trying to prove such a thing when  it seems obvious the opposite is true.

I was so intrigued, I contacted one of the authors of the study, Stephan Benoit, who was kind enough to send me a copy of the study and to spend some time talking with me about the details as well as another one they plan on publishing soon.  Here is the current study:

Gastric Bypass Surgery Attenuates Ethanol Consumption in Ethanol-Preferring Rats

One of the important things he pointed out was that the rats in this study were actually alcoholic rats to begin with.    He explained, what is important is where you start out at (as far as alcohol consumption goes), which almost seems counter-intuitive.   In mice that were already alcoholic, gastric bypass surgery appeared to actually decrease the desire to drink.   However, in the study yet to be published, they used non-alcoholic mice and found the converse to be true.

It was a real pleasure discussing this with him, and he seemed to agree that there is much more to this than the one-dimensional addiction transfer model that has been previously used to explain this phenomena.

We discussed some of the difficulties he’s run into with his research, which include getting gastric bypass patients to be honest and open about very difficult and painful issues, so that he gets accurate data.

One of my concerns was the study period.   I explained the term “honeymoon period”, and how for many of us, things went very well the first year, and that by following patients who are still in that 1-yr time frame, it may be unlikely that his data with capture the true scope of the problem.

I don’t know if it is more psychological, that we stay more strictly “on program” that first year or if it there is something bio-chemical going on and then it sort of fades after a while.  Something does seem to change after that first year though.

If any of you all have any thoughts on this, ideas on your own experience, please send me a line or a comment.   We may be able to get some assistance collecting some confidential data – so I would really appreciate your input!

L.

Posted in Uncategorized | Leave a comment

Daily Nutrient Regimen

Often I am asked what my daily vitamin regimen is.   This is what I strive to do daily.   To be honest I’m not always able to do this but I usually get close, but I also do the IV treatment which hopefully makes up for any shortfall.  I just do the best I can which is still better than I was.

Typical Vitamin Regimen
Protein Shakes (40-60 grams) in morning either whey or dried egg whites which ever suits you (egg whites upset my stomach)
Magnesium Taurate (125 mg 3x per day) or liquid Magnesium Chloride Solution (important not to get the magnesium oxide which is what is usually at the drug stores)
Vitamin D3 drops (1,000 IU/drop) at least 3 under tongue per day
Vitamin A drops (micellized (5,000 IU/drop) 1 drop under tongue per day
MultiVitamin (Good Quality) Three Servings Divided morning lunch and dinner (liquid Centrum or your favorite, recommend one without the calcium in it – take calcium separate)
Calcium Citrate (150 mg) 2 capsules 3 x per day morning lunch and dinner (this may not be enough)
Omega 3′s (look at labels) – either get liquid if you can stand it or go with capsules. You must read the labels though. A therapeutic dose for cholesterol it is EPA 1800-2160 mg and DHA 1200-1440 mg, for Depression it can be higher
Iron (Take with 1,500 mg Vitamin C – Never with Calcium)
B-12 Injection 1cc weekly (methylcobalamin not cyanocobalamin)

I also do Intravenous Micronutrient Therapy (aka Myer’s cocktail) every other week now. I started weekly but now go every 2-3 weeks.

Tyrosine (500-1500 mg) works kind of like coffee without the jitters. For me it provides clarity and focus. It’s good to take in the morning and afternoon when you need to work or study. Not if you are trying to relax. (as needed)

DL-Phenylalanine (500-1500 mg) provides a happy good feeling. It upsets my stomach, so try it and see if it works for you. I really like it but unfortunately it makes me sick.

Taurine (500-1500 mg) relaxing, calming amino acid (a lot of these hangover “cures” and such at the convenience stores put this in their product)

Product called “GabaTone” for relaxation that has valerian root, lithium, taurine …. in it

Milk Thistle is good for your liver

Posted in Uncategorized | Leave a comment

Addiction, Alcoholism, Gastric Bypass Surgery, Nutrient Deficiency and the Brain

In my last blog, I wrote about how they recently showed that gastric bypass surgery significantly increased your risk of developing alcoholism and substance abuse as well as suicide attempt and depression, much more so than merely restrictive procedures such as the lap-band.

Early on this was attributed to a psychological phenomena they called addiction transfer – theorizing that once a food addict could no longer eat they would “switch” to another substance in order to feel good.   It seemed to make sense.   Except to those of us who were experiencing it.  We knew things were different.   We felt “different”, “wrong”.  If this were truly psychological, we should see similar rates of this transfer among all weight loss surgeries:   duodenal switch, sleeve gastrectomy, lap-band, etc.

Many chemicals in the brain are responsible for that sense of well-being, your ability to feel happiness:  serotonin, dopamine, norepinephrine, endorphins.   But what about all the other nutrients your body must have in order for these chemicals to function properly?  They all work together.  Now what if those nutrients started to slowly diminish over time?  Say over the next 12-14 months? And longer?  How would you feel then?

What if you’ve suddenly achieved something you’ve yearned for, perhaps your entire life, and now find yourself having difficulty finding pleasure in things you know should find pleasure in?   Trying on new clothes?   Meeting new people?   Peoples reaction to the new you?   And what if that ability experience pleasure and joy just is not there.   You know it should be and it isn’t.   What if you start having trouble sleeping, maybe having anxiety, and you have no idea why?

And then you experience something and you feel “good” for the first time in a long time.   Maybe that something is alcohol, which if you’ve had gastric bypass, even a little bit might feel really good where before it was no big deal.   Or maybe your doctor writes you a prescription and you pop that pill and feel “good” again.  Or it might be shopping, etc…..   Or maybe you’re just one of those people that just tough it out and slog through and continue to feel awful.   The brain is incredibly amazing at associating what you need to not feel awful and is very crafty and effective at convincing you to keep it from feeling like crud all the time.

But I’m convinced that if the “feel good” chemicals in the brain had not been so deteroriated by the many months and months of depletion, so many people would not have vulnerable in the first place to this scenario.     There seems to be more understanding about how addiction works these days – the pleasure/reward pathways.   What I am hoping the scientific community starts to explore is where the breakdown is occuring.   How is this surgery creating the bio-chemical changes in our bodies that make a signficant population more vulnerable to addiction?

If this sounds at all familiar to your story, let me know.

Posted in Uncategorized | Leave a comment

Why Is Gastric Bypass Surgery Causing Addiction, Alcoholism and Suicide but the Lap-Band Procedure Isn’t?

There was a study done by Dr. Magdalena Plecka Ostlund of the Karolinska Institutet in Stockholm showing that those people that had weight loss surgeries that bypassed the intestines had much higher rates of problems with addiction, depression, alcoholism and attempted suicide than those that had the Lap-Band (or similar type).

“The gastric bypass surgery cohort had higher Hazard Ratios (HR) than the restrictive surgery cohort for substance abuse (HR, 3.8), suicide attempt (HR, 4.1), alcohol abuse (HR, 4.0), and depression (HR, 2.4). For the restrictive surgery cohort, these HRs were, respectively, 1.4, 2.4, 1.2, and 1.8, she said.”

This report has been getting quite a bit of newspaper attention regarding the alcoholism component, and though indeed alcohol abuse is a big problem, there are also significantly large increases in problems in substance abuse, depression and suicide attempts. However, the important element in this story seems to be getting lost, Why isn’t this happening to the Lap Band group? I now would like to ask, can the data be further broken down among folks that had the sleeve gastrectomy without intestinal bypass? Would the Hazard Ratios still hold then? How about for duodenal switch?

Another factor is that the data is reported using Hazard Ratios. I don’t know about you, but I wasn’t exactly familiar with the term Hazard Ratios and what they meant in medical reporting, so of course I had to look it up. How I’ve come to understand hazard ratios is that after gastric bypass surgery, there would now be a 3.8 times increase in your risk of developing substance abuse over the control group (ie., those that didn’t have surgery). A Hazard Ratio of 1 would be the equal to the control group. So, the Lap Band group is only slightly greater than the normal population with regards to risk of alcoholism and substance abuse but not nearly like the gastric bypass group is.

For those suffering from any of these, I think it certainly bears more scrutiny as to why there is such a difference between procedures, both for the sake of prevention and treatment. If the cause could be pinpointed and studied, then perhaps the tragedies could be avoided.

Posted in Uncategorized | Leave a comment

Gastric Bypass Surgery: Post-Operative Care with IV Nutrient Therapy and Injection Nutrient Therapy

I came across this interesting article.   I posted a similar one earlier when I found a local Naturopathic Doctor and started doing IV Nutrient Injection Therapy after gastric bypass surgery.

Gastric Bypass Surgery: Post-Operative Care with IV Nutrient Therapy and Injection Nutrient Therapy

By DR. Susan Williamson, NMD

With the rise of obesity in the U.S., more patients are turning to gastric bypass surgery to produce fast and dramatic weight loss. According to the Mayo Clinic, gastric bypass surgery is the most popular weight loss surgery in the United States. With gastric bypass surgery, the stomach is made smaller by reducing it to a thumb-sized pouch (15-30 mL or 1-2 tablespoons in volume), which considerably restricts the amount of food that can be eaten, as well as provide less surface area for the absorption of vitamins and minerals from food. In addition to this, the amount of hydrochloric acid (needed to absorb calcium and iron) and intrinsic factor (needed to absorb vitamin B12) produced by the stomach is greatly reduced due to its size, which also contributes to nutrient deficiencies. In addition to this, the duodenum, a major area of nutrient absorption within the intestinal tract may be bypassed depending on the type of procedure performed, further contributing to nutrient deficiencies.

Common symptoms of nutritional deficiencies are:

fatigue and weakness
hair loss and/or dry brittle hair
thin and brittle fingernails
difficulty thinking/concentrating
thinning of the skin/dry skin
softening/weakening of the bones (osteopenia/osteoporosis)
bone pain and bone deformities
muscle spasms
tooth discoloration and increased susceptibility to tooth decay
bleeding gums
increased tendency to bruise and bleed
anemia
sleep disturbances
neurological problems
pins and needles sensations in the body
permanent nerve damage
diarrhea
skin disorders
sore or swollen tongue
cracks at the edges of the mouth
swelling, usually in the legs
dehydration
decreased immune system strength, making an individual more prone to infections

Some nutrient deficiencies, if allowed to progress, can result in serious life threatening complications, so it is very important for gastric bypass patients to continue supplementing with nutrients and the best way to do this is via intravenous administration where the digestive tract is not a factor in the absorption of nutrients. With IV nutrient therapy, high doses of vitamins and minerals (much higher than what can be taken orally) can be delivered straight to the bloodstream where they are readily available to the cells for absorption and use by the body. People who have had gastric bypass surgery may also benefit from having specialty testing done at Bodhi Body Integrative Medical Centers to detect their specific nutrient deficiencies so that their particular nutrient deficiencies can be detected and therefore appropriately treated.

Common deficiencies of the fat-soluble vitamins (Vitamins A, D, E, and K) are common and these can be supplemented via intramuscular injection. Patients are at risk for developing anemia secondary to deficiencies of iron, Vitamin B12, and folate, all of which can be replenished easily via injection or IV. Calcium is a common nutrient deficiency as well due to the decreased stomach acid production in the reduced sized stomach. It is unknown whether gastric bypass patients can absorb the micronutrients selenium, zinc, and chromium, however these are included in the nutritional IVs as well as vitamin C, B12, B complex, B6, folate, calcium, magnesium, and electrolytes. Another benefit of the nutrient IVs is treatment of dehydration, which is another common symptom many suffer after gastric bypass surgery.

Patients who have nutrient deficiencies usually notice an immediate effect of feeling better after receiving a nutrient IV. If you or someone you know has had gastric bypass surgery then please contact Bodhi Body Integrative Medical Centers today so that we may assist you in replenishing your body’s nutrients and help prevent serious complications from developing and progressing. Taking oral vitamins and minerals will help some with nutrient deficiencies, however the severe deficiency that normally results after gastric bypass surgery is best treated with intravenous nutrients where gut absorption is not a factor and 100% of the nutrients is absorbed and available to the body.

Posted in Uncategorized | Leave a comment

New Study – Gastric Bypass Increases Risk for New-Onset Alcohol Abuse (Now You Tell Us?)

I recently came across this article.   It’s from a presentation at the 2011 Obesity Conference in Orlando, Florida about the phenomena of new-onset alcohol abuse after gastric bypass surgery

I actually did appreciate this article, because this was one of the few articles that did not just summarily dismiss this as a psychological transfer issue.   The fact that new-onset alcohol abuse is in fact an extreme behavioral change seems to have finally caught the attention of some scientists.  They have begun to investigate this and ask some important questions – such as when the onset began? how quickly the abuse progresses? whether or not there was a history of alcohol abuse prior to surgery?  the average age of the person when the abuse sets it, etc.,

Some of the questions I would still would like to know are, did all of these people have the Roux-en-Y, or do these findings hold true for Duodenal Switch and Sleeve Gastrectomy?

Here is the text from the article from Medscape by Steven Fox:

Gastric Bypass Increases Risk for New-Onset Alcohol Abuse

Steven Fox

The poster was presented at Obesity 2011: The Obesity Society’s 29th Annual Scientific Meeting.

“Our data underscore the need for asking patients during their preop evaluation about their use of alcohol, and again when following up after surgery,” presenter Stephanie Sogg, PhD, told Medscape Medical News. Dr. Sogg is a clinical staff psychologist at the Massachusetts General Hospital Weight Center in Boston.

Dr. Sogg said that several years ago she began hearing from patients that not only was alcohol having a far greater effect on them after surgery than before, but also that some were developing full-blown alcoholism after surgery — even if they had never had a previous problem with drinking.

And what was most intriguing, Dr. Sogg said, was that many of the people who were becoming alcoholics were middle-aged. That is long after most people begin to have alcohol-related problems. Data from the National Institute on Alcohol Abuse and Alcoholism indicate that the mean age of onset of alcohol abuse is 22 years.

“Although there’s not much in the literature on the subject of alcohol abuse following Roux-en-Y surgery, there’s quite a lot of discussion among weight loss specialists — anecdotal evidence — that this is a problem,” she said.

To find out more about a possible link, Dr. Sogg and her colleagues conducted telephone interviews with 340 patients who had undergone RYGB surgery at Massachusetts General Hospital in Boston. All procedures had been carried out at least 18 months before the survey.

About three quarters of the patients were female, and 91% were white. Mean age at the time of surgery was 46 years, and the mean time since surgery was 57 months.

Surveyors asked patients to quantify their preoperative and postoperative alcohol intake. Patients were also asked about how alcohol affected them both before and after surgery.

“We decided to ask about quantity and frequency rather than specific symptoms of alcohol abuse,” Dr. Sogg said. “That’s because we felt patients would be more comfortable reporting quantitative data rather than answering more subjective questions about their drinking.”

More than two thirds of participants said they were affected more by alcohol after surgery than before, she said.

Problem drinking was defined as consuming at least 3 drinks per day on at least 4 days per week, or having 5 or more drinks on at least 2 days per month.

“We found a significant increase in risk of new-onset postsurgical alcohol abuse among these patients,” Dr. Sogg said.

They defined “remote” problem drinking as problem drinking that had ceased more than 6 months before surgery. If patients were having drinking problems within the 6 months before surgery, that was defined as “immediate” problem drinking, Dr. Sogg explained.

About 21% of participants reported having drinking problems at some point before surgery. In all, 15% reported a remote history and 6.5% reported having an immediate problem.

Approximately 9% of participants reported a period of problem drinking after their surgery. Problem drinking after surgery was associated with younger age (P = .040), longer time since surgery (P = .001), and a higher baseline body mass index (P = .049).

“Drinking problems within 6 months prior to surgery strongly predicted problem drinking after surgery,” Dr. Sogg said. The odds ratio was 6.59 (P = .0005).

However, a remote history of problem drinking was not associated with having drinking problems after surgery (odds ratio, 1.01; P = .99), she noted.

Of particular note, Dr. Sogg said, was that 7% of patients surveyed reported new-onset problem drinking after RYGB.

However, no clinical or demographic variables were identified as predictors of new-onset drinking problems.

“In the population as a whole about 90% of alcohol problems develop before the mid-30s,” Dr. Sogg said. “The mean age of our sample was 46. So it’s troubling to find how relatively common new-onset alcohol problems were in this population of patients.”

Another observation Dr. Sogg said she has made over the years — but didn’t include in the present study — is how quickly drinking problems seem to progress in post-surgery patients. “Alcohol abuse is usually a gradual-onset problem, but in many of our patients who develop drinking problems, it seems to rapidly ramp up, escalating very quickly.”

On the basis of her study results, Dr. Sogg said clinicians need to increase their focus on the potential of alcohol-related RYGB complications. “That means better patient education, better screening, and better efforts at prevention, both before and after surgery,” she said.

“I think what this study clearly tells us is that alcohol can be a problem after surgery for some of these patients. And we especially need to watch people who had problems with drinking up to the time of surgery,” said Leslie Heinberg, PhD, director of behavioral sciences at the Bariatric and Metabolic Institute, Cleveland Clinic, Ohio, in an interview with Medscape Medical News.

She emphasized, however, that patients in the study who reported a remote history of alcohol problems before surgery were not at increased risk for postoperative drinking problems.

Dr. Heinberg, who is also associate professor at the Cleveland Clinic Lerner College of Medicine, said that in their program she and her colleagues are very careful to counsel all their patients about the physiologic changes that take place during surgery and how those changes will make patients permanently more susceptible to alcohol.

“We make sure they understand that if increased susceptibility is something that’s likely to create problems for them, they might want to reconsider having the surgery,” she said.

Dr. Sogg and Dr. Heinberg have disclosed no relevant financial relationships.

Obesity 2011: The Obesity Society 29th Annual Scientific Meeting; Abstract #21-OR. Presented October 5, 2011

Posted in Uncategorized | Leave a comment

Peripheral Neuropathy After Gastric Bypass Surgery

Peripheral Neuropathy has been increasingly on my radar, with respect to side effects related to nutrient deficiencies in gastric bypass patients.   This started for me a couple of years ago when my real good friend contacted me out of the blue.  He had gastric bypass surgery less than a year after I did from the same surgeon.   He emailed me out of concern to let me know he had been diagnosed with something called peripheral neuropathy.     How he figured this out was he was shopping in the local home improvement store and then all of a sudden experienced this extreme pain in his legs, to the point he didn’t think he would be able to make it out of the store.

What I soon learned was that peripheral neuropathy is a very serious and painful condition of the peripheral nervous system which is responsible for transmitting information from the brain and spinal cord to the rest of your body.    The Mayo Clinic found that as many as 16% of gastric bypass patients are developing nerve damage from problems associated with peripheral neuropathy.

The pain from neuropathy has been described as cutting, stabbing, crushing, burning, shooting, gnawing, or grinding, usually occurring on the extremities (arms and legs) .   Other symptoms of neuropathy include extreme numbness, paralysis, tingling, and burning.   In some cases, even just the weight of the bed sheet on the leg can trigger a pain event.    To heal or regrow nerves is a very slow and painful process.  This is definitely one of those cases – where an ounce of prevention is worth more than a pound of cure….

Think of peripheral nerves as the highways that transfer information back and forth from your extremities to the central nervous system (i.e., your big toe to your brain).    Information moves along the peripheral nerve electrically (which uses calcium, potassium and sodium as ions) and between other nerves (using neurotransmitters such as acetylcholine).  The nerve is protected by a sheath, which wraps around it and protects the fibers and keeps it from making abnormal transmissions.    When there is a breakdown anywhere in this process you can end up with a neuropathy.

There are many things that can cause neuropathies so it is often difficult to pinpoint the exact cause.   With that said, it is usually broken down to the following three causes:

  •  Acquired Neuropathies – caused by environmental factors such as toxins, trauma, illness , infection, alcoholism,  as well as poor nutrition and vitamin/nutrient deficiency
  • Hereditary Neuropathies
  • Idiopathic Neuropathies – unknown causes

In gastric bypass patients (or gastric bypass patients who have become alcoholics), the most obvious cause of acquired neuropathies is vitamin and nutrient deficiency.    Fortunately, peripheral neuropathies caused by nutrient deficiencies can be halted – even reversed – with vitamin/nutrient therapy.  The typical nutrient deficiencies associated with peripheral neuropathy are B1 (thiamine), B-12, copper or, strangely enough, an excess of B6 (pyridoxine).

Some of the nutrients that can then in turn be beneficial in alleviating the symptoms of peripheral neuropathy (if caused by vitamin/nutrient deficiency) are:

  • B-12 via injection (methylcobalamin or cyanocobalamin: methylcobalamin is the more absorbable of the two forms of B-12, so that may be the preferred form when recovering from peripheral neuropathy)
  • Vitamin B1 (thiamine)
  • Copper
  • Vitamin C
  • Multi-Mineral Supplement (that includes copper)
  • Co-Q10
  • Alpha Lipoic Acid
Posted in Uncategorized | Leave a comment